NDC 50580-414-04 TYLENOL ® FOR ADULTS COLD + FLU SEVERE Acetaminophen, Dextromethorphan HBr, Phenylephrine HCl, Guaifenesin Pain Reliever–Fever Reducer, Cough Suppressant, Nasal Decongestant, Expectorant DAY HEAD + BODY ACHES FEVER + SORE THROAT COUGH NASAL CONGESTION MUCUS + CHEST CONGESTION Actual Size 16 CAPLETS … (1969): 846. Neurology 43 Available for Android and iOS devices. (1978): 497-8, Kroenke K, Omori DM, Simmons JO, Wood DR, Meier NJ "The safety of phenylpropanolamine in patients with stable hypertension." These caplets offer acetaminophen to help reduce aches and pains while treating cold and flu symptoms, and the night-time caplets are specifically designed to provide 24-hour relief. (1985): 734-6, Humberstone PM "Hypertension from cold remedies." Helps relieve cold and flu symptoms, loosens phlegm, thins bronchial secretions and temporarily reduces a fever. (1994): 348-54, Woosley RL "Cardiac actions of antihistamines." Add to list Email Print Product description. The Nighttime caplets help relieve runny nose and sneezing along with other symptoms such as headache, cough, sore throat, nasal congestion, sinus congestion and pressure. Ann Intern Med 104 "Product Information. Whitcomb DC, Block GD "Association of acetaminopphen hepatotoxicity with fasting and ethanol use." Eur J Clin Pharmacol 22 (1992): 287-90, Shapiro SR "Hypertension due to anorectic agent." Covington TR, Lawson LC, Young LL, eds. (1983): 337-40, Chin C, Choy M "Cardiomyopathy induced by phenylpropanolamine." (1994): 1845-50, Bonkovsky HL "Acetaminophen hepatotoxicity, fasting, and ethanol." The Daytime caplets loosen phlegm and temporarily relieve cold and flu symptoms such as headache, sore throat, nasal congestion, and cough. Glaxo Wellcome, Research Triangle Park, NC. This caplet provides temporary relief of minor aches and pains, fever, headache, sore throat, nasal and chest congestion, and cough. (1986): 75-86. Neurology 37 This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). In stock at San Leandro, 15555 Hesperian Blvd, Health Concern: Cold Cough Fever Flu Headache Nasal Congestion Sinus, Inactive Ingredients: Tylenol Cold + Flu Severe Night: Anhydrous Citric Acid; Carnauba Wax; FD&C Blue No. Manufacturers, (1984): 595-9, Simons FE, Simons KJ, Frith EM "The pharmacokinetics and antihistaminic of the H1 receptor antagonist hydroxyzine." Moderate Potential Hazard, High plausibility. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. (1981): 375-9, Arnman R, Olsson R "Elimination of paracetamol in chronic liver disease." Tylenol Cold + Flu Severe Day & Night Caplets (24 ct.) provide temporary relief of cold and flu symptoms for both the daytime and nighttime. TYLENOL ® FOR ADULTS. (1993): 1313-6, Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 This convenient combo pack contains 24 caplets with 16 Daytime caplets and 8 Nighttime caplets. (Cold + Flu Severe Day): Adults and Children 12 Years and Over: Take 2 caplets every 4 hours. Br Heart J 47 (1994): Frewin DB, Leonello PP, Frewin ME "Hypertension after ingestion of Trimolets." The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. Tylenol cold and flu and severe cold and flu formula give you choice of strengths for your symptoms. (1982): 471-2, Kikta DG, Devereaux MW, Chandar K "Intracranial hemorrhages due to phenylpropanolamine." (1995): 767-73, Nelson EB, Temple AR "Acetaminophen hepatotoxicity, fasting, and ethanol." (1979): 175-6, Maher LM, Peterson PL, Dela-Cruz C "Postpartum intracranial hemorrhage and phenylpropanolamine use." The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. JAMA 244 HEAD + BODY ACHES; FEVER + SORE THROAT; COUGH; NASAL CONGESTION; MUCUS + CHEST CONGESTION; Actual Size. So if you find a current lower price from an online retailer on an identical, in-stock product, tell us and we'll match it. However, small quantities are converted by minor pathways to metabolites that can cause hepatotoxicity or methemoglobinemia. JAMA 255 (1981): 230-1, O'Connell MB, Gross CR "The effect of single-dose phenylpropanolamine on blood pressure in patients with hypertension controlled by beta blockers." Major Potential Hazard, High plausibility. (1984): 474-9, Simons FE, Frith EM, Simons KJ "The pharmacokinetics and antihistaminic effects of brompheniramine." Moderate Potential Hazard, Moderate plausibility. Electrode, Comp-afdb9d21-8645-456e-9d61-2068129d7f71, DC-wus-prod-a14, ENV-prod-a, PROF-PROD, VER-20.0.42, SHA-b0b214d15367c6464bb2ff184c24c271bef207a1, CID-541aee95-007-1778d944fe26a1, Generated: Wed, 10 Feb 2021 20:14:03 GMT, Tylenol Sinus Severe Non-Drowsy Day Relief Caplets, 24 ct. Tylenol Cold + Flu Severe Day/Night Caplets provide temporary relief of cold and flu symptoms. Dimetane (brompheniramine)." (2000): 205-13, Teh AY "Phenylpropanolamine and hypertension" Med J Aust 2 Clinical monitoring of hepatic function is recommended. call 1-877-895-3665 (toll-free) or 215-273-8755 (collect) Tylenol Cold + Flu Severe Caplets (Night) Do not take more than directed (see overdose warning) Adults and children 12 years and over: Take 2 caplets every 4 hours Swallow whole; do not crush, chew or dissolve Do not take more than 10 caplets in 24 hours Children under 12 years: Ask a doctor Other Information Store between 20-25°C (68-77°F) Do not use if blister unit is torn or broken Questions or comments? Get free shipping at $35 and view promotions and reviews for TYLENOL Cold + Flu Severe Day & Night Caplets Combo Pack (1979): 427-31, Venkataramanan R, Kalp K, Rabinovitch M, et al "Conjugative drug metabolism in liver transplant patients." J Med Chem 11 Giving Tylenol Cold-Flu Severe Day Liquid to a child under 12. management or monitoring precaution: Use weight based dosing in children less than 12 years. Moderately clinically significant. Tylenol (acetaminophen)." These effects are usually transient and slight but may be significant with dosages higher than those normally recommended. Tylenol Cold + Flu Severe Day: Carnauba Wax; Croscarmellose Sodium; D&C Yellow No. (1979): 1110-1, Bernstein E, Diskant BM "Phenylpropanolamine: a potentially hazardous drug." The aspartame/phenylalanine content should be considered when these products are used in patients who must restrict their intake of phenylalanine (i.e. Value pack of Tylenol Cold + Flu Severe Daytime Relief Liquid Medicine & Nighttime Liquid Medicine. In patients with anatomically narrow angles or narrow-angle glaucoma, pupillary dilation can provoke an acute attack. Caution should be used when prescribing antitussives such as dextromethorphan and benzonatate in patients with psychiatric or emotional conditions. DAY. Int J Obes 9 (1986): 2636-7, Kartsonis A, Reddy KR, Schiff ER "Alcohol, acetaminophen, and hepatic necrosis." Get specific details about this product from customers who own it. (1993): 825-7, Finton CK, Barton M, Chernow B "Possible adverse effects of phenylpropanolamine (diet pills) on sympathetic nervous system function--caveat emptor!" (1980): 60-1, Gordon RD, Ballantine DM, Bachmann AW "Effects of repeated doses of pseudoephedrine on blood pressure and plasma catecholamines in normal subjects and in patients with phaeochromocytoma." 24-count combo pack of Tylenol Cold + Flu Severe Day/Night Caplets for multi-symptom cold and flu symptom relief. The Daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. Lake CR, Zaloga G, Bray J, Rosenberg D, Chernow B "Transient hypertension after two phenylpropanolamine diet aids and the effects of caffeine: a placebo-controlled follow-up study." Moderate Potential Hazard, High plausibility. 1 aluminum lake, flavor, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polysorbate 80, potassium sorbate, powdered cellulose, pregelatinized starch, sodium benzoate, sodium citrate dihydrate, sodium starch glycolate, sucralose, titanium dioxide, Tylenol Cold + Flu Severe Caplets (Day) Do not take more than directed (see overdose warning) Adults and children 12 years and over: Take 2 caplets every 4 hours Swallow whole; do not crush, chew or dissolve Do not take more than 10 caplets in 24 hours Children under 12 years: Ask a doctor Other Information Each caplet contains: sodium 3 mg Store between 20-25°C (68-77°F) Do not use if blister unit is torn or broken Questions or comments? Schering-Plough, Liberty Corner, NJ. Moderate Potential Hazard, Moderate plausibility. (Cold + Flu Severe Night): Adults and Children 12 … In patients with other forms of glaucoma, mydriasis may occasionally increase intraocular pressure. Drug Intell Clin Pharm 22 (1983): 71-3, Wiener I, Tilkian AG, Palazzolo M "Coronary artery spasm and myocardial infarction in a patient with normal coronary arteries: temporal relationship to pseudoephedrine ingestion." Therapy with antihistamines should be administered cautiously, if at all, in patients with preexisting conditions that are likely to be exacerbated by anticholinergic activity, such as urinary retention or obstruction; angle-closure glaucoma, untreated intraocular hypertension, or uncontrolled primary open-angle glaucoma; and gastrointestinal obstructive disorders. The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. "Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine." (1984): 180-1, Wooten MR, Khangure MS, Murphy MJ "Intracerebral hemorrhage and vasculitis related to ephedrine abuse." There is 1 alcohol/food interaction with Tylenol Cold and Flu Severe Day & Night (acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / … Tylenol Cold + Flu Severe Day/Night Caplets provide temporary relief of cold and flu symptoms. (1985): 2019-23, O'Dell JR, Zetterman RK, Burnett DA "Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic." Moderate Potential Hazard, Moderate plausibility. Isolated instances of bizarre behavior, including mental confusion and visual hallucinations have been reported in patients taking antitussives, specially when combined with other prescribed drugs such as monoamine oxidase inhibitors. Tylenol Cold and Flu work, both daytime and night time, regular cold or flu, or severe formula cold and flul. The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. (1974): 1066-76, Albert KS, Hallmark MR, Sakmar E, Weidler DJ, Wagner JG "Pharmacokinetics of diphenhydramine in man." The maximum daily dose of this product is 10 caplets (3,000 mg of acetaminophen in 24 hours with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product. Applies to: Liver Disease. West J Med 142 10 Aluminum Lake; Flavor; Hydroxypropyl Cellulose; Hypromellose; Magnesium Stearate; Microcrystalline Cellulose; Polyethylene Glycol; Pregelatinized Starch; Sucralose; Titanium Dioxide; Each Caplet Contains: Sodium 3 mg, Tylenol Cold + Flu Severe Caplets (Day) Active ingredients (in each caplet) Purpose Acetaminophen 325 mg...............................................Pain reliever/fever reducer Dextromethorphan HBr 10 mg.....................................Cough suppressant Guaifenesin 200 mg.....................................................Expectorant Phenylephrine HCl 5 mg..............................................Nasal decongestant Inactive ingredients carnauba wax, croscarmellose sodium, D&C yellow no. Sandoz Pharmaceuticals Corporation, East Hanover, NJ. Free shipping free returns cash on delivery available on eligible purchase can cause hepatotoxicity or methemoglobinemia mcclain CJ Kromhout. 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