Carboxylic acids donate hydrogen ions if a base is present to accept them. In addition to the Thermodynamics Research Center (TRC) data available from this site, much more physical and chemical property data is available from the following TRC products: Registration dossier . It is also used as an anti-oxidant, as a mordant (a substance that helps dyes stick to fabric), and as a buffering agent (helps maintain a particular acidity or alkalinity). The trans isomer possesses a dipole moment. United States Pharmacopeia (USP) Reference Standard, +86-21-33585366 E-mail：sales03@shyrchem.com, Fumaric acid, 94%, contains ca. MDL number MFCD00002700. Get info of suppliers, manufacturers, exporters, traders of Fumaric Acid for buying in India. Ignition % = 0.1 . Chroma (in 5% ethanol) Hazen ≤15. Fumaric acid is an organic compound with the formula HO2CCH=CHCO2H. Weight Average: 116.0722 Monoisotopic: 116.010958616 Chemical Formula C 4 H 4 O 4 Synonyms (2E)-2-butenedioic acid (E)-2-butenedioic acid; Fumaricum acidum All rights reserved, The mailbox will be used as the login user name and retrieve the password, (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), 1-Boc-4-(4-methoxycarbonylphenyl)piperazine, 4-[4-(tert-Butoxycarbonyl)piperazino]benzoic acid, food grade high quality fumaric acid cas 110-17-8, LD50 orally in Rabbit: 9300 mg/kg LD50 dermal Rabbit 20000 mg/kg, Fumaric acid The structure of both acids are: Reason. Chemsrc provides fumaric acid(CAS#:110-17-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. C(=C/C(=O)O)\C(=O)O Maleic acid, the cis isomer (I), has a melting point of 130°C and a boiling point of 160°C; fumaric acid, the trans isomer (II), has a melting point of 286°C and a boiling point of 290°C. From Wikipedia. Their reactions with bases, called "neutralizations", are accompanied by … In this method, maleic acid is transformed into fumaric acid through the process of heating the maleic acid in 12 M hydrochloric acid solution. CopyCopied, InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+ Fumaric acid or trans-butenedioic acid is the chemical compound with the formula HO 2 CCH=CHCO 2 H. This white crystalline compound is one of two isomeric unsaturated dicarboxylic acids, the other being maleic acid. tested according to USP/NF, Fumaric acid HELP! DL-malic acid … ... Melting/freezing point at 101 325 Pa provides information on the substance melting/freezing point in °C at a pressure of 101 325 Pa. CopyCopied, CSID:10197150, http://www.chemspider.com/Chemical-Structure.10197150.html (accessed 22:25, Jan 7, 2021) These properties are due to the intramolecular hydrogen bonding of maleic acid molecules. It has a fruit-like taste and has been used as a food additive. 5% starch. Arsenic (base on As) PPM ≤3. Find here online price details of companies selling Fumaric Acid. Other Information. Fusion (melting) point: Δ c H° solid: Enthalpy of combustion of solid at standard conditions: Δ f H° liquid: Enthalpy of formation of liquid at standard conditions: Δ f H° solid: Enthalpy of formation of solid at standard conditions: Δ r H° Enthalpy of reaction at standard conditions: Δ sub H: Enthalpy of sublimation eCl@ss 39021709 . A. B. A white solid, fumaric acid occurs widely in nature. A butenedioic acid in which the C2C double bond has E geometry. Its acidity is 2.5 times of that of citric acid… Its melting point is 135 °C, and it is a much lower value compared to the melting point of fumaric acid. Melting point/range: 287 °C; 3.6. CopyCopied, VZCYOOQTPOCHFL-OWOJBTEDSA-N You can also browse global suppliers,vendor,prices,Price,manufacturers of Fumaric acid(110-17-8). Figure 01: Structure of Maleic Acid. Above this temperature, the compound decomposes. 75 hospitalized patients (42 female, 33 males, age 20 to 91) were dosed with 500 mg fumaric acid/day for one year. Combustible. C. Why does maleic acid react with magnesium metal? trans-1,2-Ethylenedicarboxylic. In fumaric acid the carboxylic acid groups are trans (E) and in maleic acid they are cis (Z). Fumaric acid is used as a flavoring, because it is the sourest tasting of the organic acids.Three parts of fumaric acid are as sour as five parts of citric acid. This Safety Data Sheet of Fumaric Acid is based upon a limited review of Foodchem Internation Corporation files and standard Toxicological handbooks. - Find MSDS or SDS, a COA, data sheets and more information. fumaric acid ,Butenedioic acid , Allomaleic acid , Boletic acid , Donitic acid , Lichenic acid. At last,Fumaric acid(110-17-8) … The dipole moment of maleic acid... See full answer below. The melting point of fumaric acid is 287 ° C. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The substance has a more sour flavor than citric acid, another common food additive. It is an intermediate metabolite in the citric acid cycle. Color ( 5% ethanol) # = 15 . trans-butenedioic acid Synonyms: fumaric acid Physical appearance: colorless monoclinic crystals Empirical formula (Hill's system for organic substances): C 4 H 4 O 4 Structural formula as text: HOOCCH=CHCOOH Molar/atomic mass: 116.07 Melting point (°C): 287 Solubility (g/100 g of solvent): acetone: 1.29 (20°C) acetone: 1.72 (29.7°C) Fumaric acid may be used in the preparation of L-Lysine-fumaric acid crystals. Why does maleic acid have a lower melting point that fumaric acid? Fumaric acid occurs naturally in fumitory, bolete mushrooms, lichen and Iceland moss. oC. Fumaric acid for synthesis. 286~302 . Solubility (25℃) g/100gwater ≥1.0. Maleic acid or cis-butenedioic acid is an organic compound that is a dicarboxylic acid, a molecule with two carboxyl groups. Fumaric acid is odorless with a specific and intense sour, about 1.5 times that of citric acid. Organic Compound; Food Toxin; Metabolite; Lachrymator; Animal Toxin; Natural Compound, ORL-RAT LD50 9300 mg kg-1 , IPR-MUS LD50 200 mg kg-1, SKN-RBT LD50 20 mg kg-1. adenosine ribonucleotides de novo biosynthesis, aerobic respiration III (alternative oxidase pathway), fumarate[in] + a menaquinol[membrane] -> succinate[in] + a menaquinone[membrane], fumarate[in] + a rhodoquinol[membrane] -> succinate[in] + a rhodoquinone[membrane], fumarate[in] + an electron-transfer quinol[membrane] -> succinate[in] + an electron-transfer quinone[membrane], L-arginine biosynthesis I (via L-ornithine), L-arginine biosynthesis II (acetyl cycle), succinate[in] + a ubiquinone[membrane] -> fumarate[in] + an ubiquinol[membrane], succinate[in] + an electron-transfer quinone[membrane] -> fumarate[in] + an electron-transfer quinol[membrane], succinate[mitochondrial lumen] + a ubiquinone[mitochondrial lumen] -> fumarate[mitochondrial lumen] + an ubiquinol[mitochondrial lumen], superpathway of glyoxylate cycle and fatty acid degradation, (S)-dihydroorotate + fumarate -> orotate + succinate, 4-fumaryl-acetoacetate + H2O -> fumarate + acetoacetate + H+, 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole -> 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate + fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole -> fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, adenylo-succinate -> AMP + fumarate + fumarate + AMP, canavaninosuccinate -> L-canavanine + fumarate, fumarate[in] + 2 H+[in] + 2 e-[membrane] -> succinate[in], L-arginino-succinate -> L-arginine + fumarate. EC Number 203-743-0. Fumaric Acid is an essential ingredient in plant life. A butenedioic acid in which the C2C double bond has E geometry. It is an intermediate metabolite in the citric acid cycle. Fumaric acid for synthesis. Ash content % ≤0.03. +Add Attachment Melting point will be higher in case of intermolecular hydrogen bonding. Maleic acid dissolves readily in water and ether; fumaric acid is practically insoluble in water and nearly all organic solvents. Beilstein/REAXYS Number 605763 . CAS 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH. No effects on various blood and urine parameters and no change in liver function was observed.Fumaric acid is not expected to accumulate since it plays a role in normal body Decomposes at around 230 C. Incompatible with strong oxidizing agents, bases, reducing agents. Fumaric acid can form intermolecular hydrogen bonds (strong) while maleic acid forms intramolecular hydrogen bonds (weak), hence fumaric acid has higher boiling point than maleic acid." Molecular Weight 116.07 . Fumaric acid is a common food additive included in many processed foods to keep them stable and to add tartness. Fumaric acid CAS 110-17-8 EMPROVE® ESSENTIAL NF,JPE - Find MSDS or SDS, a COA, data sheets and more information. Maleic Acid % = 0.1 . Salt has a melting point of 287 °C, the boiling point of 290 °C at temperatures above 200 °C. Linear Formula HOOCCH=CHCOOH . D. Why do both react with bicarb? Visit ChemicalBook To find more Fumaric acid(110-17-8) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. It will lose water when heated to 230 °C and will become maleic anhydride. The crystals were prepared by solvent evaporation and fully characterised by thermal and diffrac It can be used as acidulant, acidity regulator, acidifier, thermal-oxidative resist auxiliary, curing accelerant and spice. Why is maleic acid more soluble in water than fumaric acid? Melting point of fumaric acid is much higher than that of maleic acid. PubChem Substance ID 57648052 Articles of fumaric acid are included as well. 12.1. It is used in the manufacture of medicines, drinks, food, animal feed, cleansing agents, unsaturated polyester, alkyd resins, and printing inks. Fumarate can also refer to the C 4H 2O 4 ion (in solution). ... Fumaric Acid is fully biodegradable and the products of degradation are not toxic. Its E number is E297. CopyCopied, Validated by Experts, Validated by Users, Non-Validated, Removed by Users, Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, Predicted data is generated using the US Environmental Protection Agency’s EPISuite™, Click to predict properties on the Chemicalize site, For medical information relating to Covid-19, please consult the, https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:18012, ACD/Labs Percepta Platform - PhysChem Module, US Environmental Protection Agency’s EPISuite™, Compounds with the same molecular formula, Search Google for structures with same skeleton. CAS 110-17-8, EC Number 203-743-0, chemical formula HOOCCHCHCOOH. E. In thymol blue, why does maleic acid produce a reddish color while fumaric acid … The melting point of maleic acid (139–140 °C) is also much lower than that of fumaric acid (287 °C). They react in this way with all bases, both organic (for example, the amines) and inorganic. FUMARIC ACID is a carboxylic acid. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The username will be used as the login user name and retrieve the password, Copyright 2017 © ChemicalBook. Heavy metal (base on Pb) PPM ≤10. Fumaric acid has been used as a standard for the quantitative determination of phenolic compounds in nettle samples by HPLC. The salts and esters are known as fumarates. Stable at room temperature. Melting point-286-289. Fumaric acid ≥99% CAS Number 110-17-8. Fumaric acid has a fruit-like taste. 12. Usage: The solubility of fumaric acid-CWS is 65% higher than that of original fumaric acid. - Find MSDS or SDS, a COA, data sheets and more information. Main Function and Purpose: Fumaric acid has bacteriostatic and antiseptic function. Melting Point . This study investigates the relationships between the supramolecular structure and the solubility and melting point of six multicomponent crystals involving fumaric acid (FUM series) and adipic acid (ADI series). Fumaric Acid is a white crystalline chemical compound widely found in nature. 298-300 °C (Literature, Sublimes) Indofine [020723] 299 °C (Sublimes) Alfa Aesar 230 °C (Decomposes) OU Chemical Safety Data (No longer updated) More details 132-136 °C Alfa Aesar [A14596] : 138 °C Jean-Claude Bradley Open Melting Point Dataset 14807: 130.5 °C Jean-Claude Bradley Open Melting Point Dataset 25955: 299.5 °C Jean-Claude Bradley Open Melting Point Dataset 28127, 28128 Exporters, traders of fumaric acid occurs widely in nature manufacturers of fumaric acid is based upon limited... Fumaric acid, Boletic acid, Donitic acid, a molecule with two groups. As a food additive the fumaric acid melting point of fumaric acid is fully biodegradable and the products of degradation are toxic. 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